Applied Materials, Inc. (AMAT) vs Merck & Co., Inc. (MRK)

Applied Materials Inc. is the world’s largest manufacturer of semiconductor wafer fabrication equipment, with a broad portfolio covering nearly every segment of the WFE ecosystem. The company holds a leading market share in deposition technologies, which involve adding new material layers to semiconductor wafers. Applied Materials has greater exposure to general-purpose logic chips produced by integrated device manufacturers and foundries. Its customer base includes some of the world’s largest chipmakers, such as TSMC, Intel, and Samsung.

Merck & Co., Inc. develops pharmaceutical products across multiple therapeutic areas, including cardiometabolic disorders, oncology, and infectious diseases. In cancer treatment, its immuno-oncology portfolio, led by Keytruda, represents a significant driver of total revenue. The company also maintains a strong vaccines business focused on preventing pediatric illnesses, alongside Gardasil for human papillomavirus. In addition, Merck markets animal health products. Geographically, 47% of the company’s sales come from its U.S. human health segment, which includes pharmaceuticals and vaccines.