Vertex Pharmaceuticals Inc. is a global biotechnology company focused on discovering and developing small-molecule medicines for serious diseases. Its leading products include Kalydeco, Orkambi, Symdeko, Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, an area in which Vertex therapies continue to represent the global standard of care. The company has expanded its portfolio with Casgevy, a gene-editing treatment for beta thalassemia and sickle cell disease, and Journavx, a non-opioid medicine approved for moderate-to-severe acute pain in adults. Vertex is also advancing small-molecule inhibitors targeting APOL1-mediated kidney diseases and exploring cell therapies aimed at delivering a potential functional cure for type 1 diabetes.